ANEMIAS AND OTHER RED CELL DISORDERS

Key Features:
1. Imbued with the clinical expertise of the leading lights of ¿red cell¿ hematology.
2. Each chapter a consistent format, promulgating a unified patient management strategy.
3. Full spectrum of coverage on all acute, congenital, and chronic anemias, and al other red cell disorders.
4. Covers all treatment modalities¿Chemotherapy, monoclonal antibodies, stem and hematopoietic stem cell transplantation.

Tabla de Contenidos

I. Anemia: Overview II. Severe Anemias with Minimal Symptoms

A. Adults 1. Nutritional Anemias

a) Iron Deficiency
b) Folate Deficiency
c) Cobalamin Deficiency 2. Hormone Deficiency
a) Erythropoietin Deficiency

(1) Renal Dysfunction
(2) Pure Erythropoietin Deficiency

3. Stem Cell Dysfunction

a) Myelodysplasia
b) Pure Sideroblastic Anemia
c) Pure Red Cell Aplasia
d) Paroxysmal Nocturnal Hemoglobinuria 4. Immune Dysregulation
a) Autoimmune hemolytic anemia

B. Children 1. Nutritional Anemias 2. Hormone Deficiency 3. Membrane Disorders

a) Hereditary spherocytosis
b) Hereditary pyropoikilocytosis 4. Enzymopathies
a) G6PD Deficiency
b) Pyruvate Kinase Deficiency 5. Hemoglobinopathy
a) Thalassemia syndromes 6. Congenital Dyserythropoietic Anemia 7. Diamond-Blackfan Anemia 8. Immune Dysregulation
a) Autoimmune hemolytic anemia
b) Isoimmune hemolysis of the newborn III. Mild to Moderate Anemias with Minimal Symptoms

A. Adults 1. (Same as Severe) 2. Hemoglobinopathies

a) Thalassemia syndromes
b) Sickle cell syndromes 3. Membrane Disorders
a) Hereditary spherocytosis
b) Hereditary elliptocytosis 4. Enzymopathies
a) G6PD deficiency
b) Pyruvate Kinase deficiency 5. Immune Dysregulation
a) Autoimmune hemolytic anemia
b) Drug-induced hemolysis 6. Anemia of Chronic Inflammation
a) Malignancy¿Solid Tumors
b) Leukemia and Lymphoma
c) Chemotherapy-Induced Anemia

D) HIV 7. (Same as Severe) 8. Sideroblastic Anemia 9. Anemia of Chronic Inflammation IV. Anemias with Prominent Symptom Complexes

A. Adults 1. Hemoglobinopathies

a) Sickle cell syndromes
b) Thalassemia syndromes B. Children 1. Hemoglobinopathies
a) Sickle cell syndromes
b) Thalassemia syndromes

Biografía autor/es

Kenneth Bridges, MD Professor of Medicine Harvard Medical School Vice-Chairman,Division of Hematology Brigham and Women's Hospital Boston, MA