KLIPPEL RHEUMATOLOGY E-DITION, 2 VOLS.

Reviews

"In terms of presentation and visual impact has no serious rivals Annals of Rheumatic Disease paves a new road in its use of visual and organisational techniques NEJM Rheumatology is a user friendly, beautiful addition to the rheumatologist s library"
-- Arthritis and Rheumatism

Features

• Uses a consistent organisation to ensure rapid access to essential information-offering a definition for each disease followed by information on epidemiology, pathophysiology, clinical findings, differential diagnosis, and management
• Offers a highly visual layout that makes the content easy to grasp and retain

What's New

• In-depth discussions on the hottest topics, including genetics and the latest targeted therapies
• Evidence-based, clinically oriented material integrates "need-to-know" basic science with current clinical practice guidelines.
• Emphasis on orthopaedics and non-drug therapy.
• 58 brand-new chapters - with all other chapters carefully revised or completely rewritten.
• User-friendly format, with a consistent organization throughout from chapter to chapter and management algorithms for easy reference.
• Lavish illustrations-with more than 1,600 full-colour photographs, tables, and charts.

New e-dition!

The website features fully searchable contents of RHEUMATOLOGY, 3rd Edition, plus...

• Monthly updates to content news from MD Consult and RheumAlert links to MEDLINE and links to related web sites such as ACR, EULAR, PANLAR, Jointandbone.org, the Arthritis Foundation, ASBMR, and IBMS.
• Additional images that may be downloaded into PowerPoint® slides videos of injection techniques and patient information material.
• References and evidence-based summaries outcomes measurement assessment tools derived from Klippel: RHEUMATOLOGY, 2nd Edition guidelines from the ACR and other rheumatology organizations.
• Case of the month and self-testing tools.
  

Contents

VOLUME ONE

SECTION I: INTRODUCTION TO THE STUDY OF RHEUMATIC DISEASES

1. History of rheumatic diseases

2. Classification of rheumatic diseases

3. Epidemiologic concepts and rheumatology

4. Principles of outcome assessment

5. The worldwide economic and functional impact of rheumatic disease

6. The provision of rheumatologic services

7. Principles of health-economics and application to rheumatic disorders


SECTION II: THE SCIENTIFIC BASIS OF RHEUMATIC DISEASE

8. The musculoskeletal system

9. Joint physiology

10. Biomechanics

11. Principles and techniques of molecular biology

12. Genetic factors in rheumatic disease

13. Principles of Immunology

14. Tissue destruction and repair

15. Neuropeptides and free radicals

16. Inflammation

17. The synovium

SECTION III: EVALUATION, SIGNS AND SYMPTOMS

18. History and physical Examination

19. Pattern Recognition Arthritis

20. Laboratory tests in rheumatic disorders

21. Testing for ANA and ANCA - Diagnostic value and pitfalls

22. Synovial fluid analysis

23. Aspiration and injection of joints and periarticular tissues

24. Minimally invasive procedures

25. Imaging principles and techniques

26. Skin and rheumatic disease

27. The eye and rheumatic disease

28. The heart in rheumatic disease

29. The lung in rheumatic disease

30. Gastrointestinal tract and rheumatic disease

31. The kidney and rheumatic disease

SECTION IV: PRINCIPLES OF MANAGEMENT

32. Principles of management of patients with rheumatic disease

33. Health promotion and patient education for people with arthritis

34. Principles of pain and pain management

35. NSAIDs

36. Systemic corticosteroids in rheumatology

37. Intra-articular and intralesional therapy

38. DMARDS 1 Antimalarials and gold, d-penicillamine

39. DMARDS 2 (sulfasalazine, dapsone)

40. DMARDS 3 (methotrexate)

41. DMARDS 41 (leflunomide)

42. Immunosuppressives (chlorambucil, cyclosporin, cytoxan, imuran, mofetil, tacrolimus)

43. Immunotherapies Tcell, Bcell, complement

44. Thalidomide

45. Cytokine neutralizers

46. Emerging therapeutic targets

47. Antibiotics

48. Drugs and Pregnancy

49. Alternative and complementary medicine

50. Principles of rehabilitation

51. Principles of arthritis surgery

SECTION V: REGIONAL AND WIDESPREAD PAIN

52. Anatomy and biomechanics of the spine

53. Neck pain

54. Low back pain and lumbar spinal stenosis

55. The shoulder

56. The elbow

57. The wrist and hand

58. The hip

59. The knee

60. The ankle and foot

61. Temporomandibular pain syndrome

62. Fibromyalgia and related syndromea

63. Entrapment neuropathies and compartment syndromes

64. Algodystrophy/reflex sympathetic dystrophy syndrome

65. Sports medicine: the clinical spectrum of injury

SECTION VI: RHEUMATOID ARTHRITIS AND OTHER SYNOVIAL DISORDERS

66. History

67. Classification and epidemiology

68. Clinical features of rheumatoid arthritis

69. Extrarticular features of rheumatoid arthritis and systemic involvement

70. Adult Still's disease

71. Imaging of rheumatoid arthritis

72. Genetics of the major histocompatibility complex in rheumatoid arthritis

73. Animal models of arthritis

74. Autoantibodies in rheumatoid arthritis

75. Cellular immunity in rheumatoid arthritis

76. Angiogenesis in rheumatoid arthritis

77. Rheumatoid synovitis and pannus

78. Evaluation and management of early inflammatory polyarthritis

79. Evaluation and outcome of the patient with established rheumatoid arthritis

80. Management of rheumatoid arthritis: synovitis

81. Management of extra-articular disease and complications

82. Multidisciplinary approach to rheumatoid arthritis

SECTION VII: PEDIATRIC RHEUMATOLOGY

83. History

84. Classification and epidemiology of juvenile inflammatory arthritis

85. Clinical features and special problems and presentations in children

86. Evaluation of muskuloskeletal complaints in children

87. Legg-Perthes and other hip diseases in children

88. Etiology and pathogenesis JCA

89. JRA Management

90. Connective tissue diseases in children

91. Rehabilitation and psychosocial issues


VOLUME TWO

SECTION VIII: INFECTION-RELATED RHEUMATIC DISEASES

INFECTION

92. Microorganisms and the locomotor system

93. Septic arthirits and osteomyelitis

94. Gonococcal arthritis

95. Mycobacterial, brucella, fungal and parasitic arthritis

96. Lyme disease and syphilitic arthritis

97. Viral arthritis

98. Rheumatic aspects of human immunodeficiency virus infection and other immunodeficient states

99. Acute rheumatic fever

SECTION IX: SPONDYLOARTHROPATHIES

100. History

101. Classification of spondyloarthropathy

102. Epidemiology of ankylosing spondylitis

103. Clinical features of ankylosing spondylitis

104. Etiology and pathogenesis of ankylosing spondylitis

105. Ankylosing spondylitis: Imaging

106. Ankylosing spondylitis: pathology

107. Ankylosing spondylitis: management

108. Reactive arthritis: etiology and pathogenesis

109. Reactive arthritis: clinical features and treatment

110. Psoriatic arthritis: clinical features

111. Psoriatic arthritis: etiology and pathogenesis

112. Psoriatic arthritis: management

113. Enteropathic arthropathies - diagnosis and treatment

114. Enthesopathy

SECTION X: CONNECTIVE TISSUE DISORDERS

SYSTEMIC LUPUS ERYTHEMATOSUS

115. History

116. Epidemiology and classification of SLE

117. Immunopathology

118. Genetics of lupus

119. The complement system

120. Autoantibodies in SLE

121. Cellular immunology

122. Clinical features

123. Neonatal lupus

124. Drug-induced lupus

125. Assessing disease activity and outcome in SLE

126. Treatment - skin, joints, serositis, pneumonitis, constitutional etc

127. Treatment - renal involvement

128. Severe SLE

129. Pregnancy in SLE

130. Sjögren's syndrome

131. Antiphospholipid syndrome: diagnosis and management

SYSTEMIC SCLEROSIS

132. History of epidemiology and outcome measurements of scleroderma

133. Clinical features

134. Etiology and pathogenesis

135. Management

136. Raynaud's phenomenon

137. Localized scleroderma and idiopathic and environmentally induced scleroderma variants


INFLAMMATORY MUSCLE DISEASE

138. Etiology and pathogenesis

139. Clinical features of inflammatory disease

140. Management of Inflammatory Muscle Disease

141. Inflammatory and metabolic myopathies

142. Overlap syndromes

SECTION XI: THE VASCULITIDES

143. Overview of the inflammatory vascular diseases

144. Biology of the vascular endothelium

145. Immunopathogenesis of vasculitis

146. Polyarteritis - polyarteritis nodosa and microscopic polyangiitis
147. Polymyalgia rheumatica and giant cell arthritis
148. Wegener's granulomatosis and lymphomatoid granulomatosis

149. Churg-Strauss syndrome

150. Takayasu's arteritis

151. Behçet's syndrome

152. Kawasaki disease

153. Henoch-Schönlein purpura

154. Panniculitis

155. Cutaneous vasculitis

156. Cryoglobulinemia

157. Primary angiitis of the central nervous system

SECTION XII: OTHER SYSTEMIC ILLNESSES

158. Familial Mediterranean fever

159. Sarcoidosis

160. Relapsing polychondritis

161. Miscellaneous arthropathies including synovial tumors and foreign body synovitis

162. Hypertrophic osteoarthropathy

163. Cogan's Syndrome

SECTION XIII: OSTEOARTHRITIS AND RELATED DISORDERS

OSTEOARTHRITIS AND RELATED DISORDERS

164. Epidemiology and classification

165. Clinical features

166. Osteoarthritis: pathogenesis

167. The genetics of osteoarthritis

168. Imaging

169. Pathology

170. Evaluation of the patient with osteoarthritis and measurement of outcomes

171. Management of limb joint osteoarthritis

172. Diffuse idiopathic skeletal hyperostosis

173. Neuropathic arthropathy

174. Osteonecrosis

SECTION XIV: CRYSTAL-RELATED ARTHROPATHIES

175. Epidemiology, classification and history of crystal-related arthropathies

176. Etiology and pathogenesis of gout

177. Clinical features of gout

178. The management of gout

179. Calcium pyrophosphate dihydrate - crystal deposition disease
(pseudogout)

180. Basic calcium phosphate crystal deposition disease

181. Other crystal associated arthropathies

SECTION XV: ENDOCRINE AND HEMOGLOBIN-RELATED ARTHRITIS AND STORAGE DISEASES

182. Acromegaly

183. Rheumatologic manifestations of thyroid diseases

184. Diabetes mellitus

185. Dialysis arthropathy

186. Primary hyperlipidemias and xanthomatosis

187. Hemophilia and other bleeding disorders

188. Joint and bone lesions in hemoglobinopathies

189. Hemochromatosis

190. Ochronosis

191. The amyloidoses

SECTION XVI: METABOLIC BONE DISEASES

192. Bone structure and function

193. Investigations of bone: biochemical markers

194. Epidemiology, classification and history of
Osteoporosis

195. Investigations of bone: imaging

196. Osteoporosis: pathogenesis

197. Osteoporosis: clinical features

198. Management of osteoporosis

199. Glucocorticoid-induced osteoporosis

200. Rickets and osteomalacia

201. Hyperparathyroidism

202. Renal bone disease

203. Paget's disease of bone

SECTION XVII: HEREDITABLE DISEASE AND TUMORS OF BONE AND CONNECTIVE TISSUE

204. Gaucher's disease

205. Mucopolysaccharidoses

206. Heritable collagen disorders

207. Hypermobility syndrome

208. Skeletal Dysplasias

209. Tumors of bone