IDIOPATHIC PULMONARY FIBROSIS

Key topics include the role of polymorphonuclear leukocytes in the pathogenesis of pulmonary fibrosis, and current treatment options, including medical therapy and lung transplantation.

Table of Contents

• Epidemiology of Idiopathic Pulmonary Fibrosis
  David B. Coultas and Richard Hubbard
• Genetics of Idiopathic Pulmonary Fibrosis and Other Variants
  David A. Schwartz, Ganesh Raghu, and Momen M. Wahidi
• Clinical Features and Differential Diagnosis of Idiopathic Pulmonary Fibrosis (IPF)
  Talmadge E. King, Jr. and David Morris
• Pathology of Usual Interstitial Pneumonia (UIP)
  William D. Travis
• Non-Specific Interstitial Pneumonia
  Fernando Martinez, William Travis, and Joseph P. Lynch
• Physiology of Idiopathic Interstitial Pneumonia (Pulmonary Function and Exercise Testing)
  Fernando Martinez, Kevin Flaherty, Vibha Lama, and Joseph P. Lynch
• Radiology of Idiopathic Interstitial Fibrosis (Chest Radiographs, HRCT)
  David Zisman, Kevin Flaherty, Ella Kazerooni, Joseph P. Lynch, and Fernando Martinez
• Other Imaging Techniques for Idiopathic Interstitial Pneumonias (Radionuclide Studies, PET Scans)
  R. M. du Bois and Suveer Singh
• Bronchoalveolar Lavage: Role in Diagnosis or Staging of Idiopathic Interstitial Fibrosis
  Robert P. Baughman and Ulrich Costabel
• Pulmonary Fibrosis Complicating Connective Tissue Disease
  Athol Wells
• Cytokine Phenotypes and the Progression of Chronic Pulmonary Fibrosis
  Steven L. Kunkel
• CXC Chemokines and Angiogenic Factors in the Pathogenesis of Pulmonary Fibrosis
  Robert Strieter, John Belperio, and Michael Keane
• Role of Polymorphonuclear Leukocytes in the Pathogenesis of Pulmonary Fibrosis
  Eric White and Theodore Standiford
• Integrins in Pulmonary Fibrosis
  Dean Sheppard and Laura Koth
• Oxidants and Antioxidants in IPF
  Jürgen Behr
• Fibrin Turnover in Pulmonary Fibrosis
  Steven Idell
• Arachidonic Acid Metabolite: Potential Mediators and Therapeutic Targets in Fibrotic Lung Disease
  Marc Peters-Golden
• Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Pulmonary Fibrosis
  Moses Selman and Annie Pardo
• Extracellular Matrix
  Ronald Goldstein, David C. Rishikof, and Dennis A. Ricupero
• Role of Fibroblast and Myofibroblast in IPF
  Sem Phan and Mehrnaz Gharaee-Kermani
• Fibroblast Growth Factors (FGF)
  Peter Bitterman and Hyun Kim
• Role of Type II Alveolar Epithelial Cells
  Robert J. Mason and Josh Portnoy
• Surfactant Apoproteins in the Pathogenesis of Pulmonary Fibrosis
  Hiroki Takahashi
• Bronchiolar Epitherlium in IPF/UIP
  Marco Chilosi and Gianpietro Semenzato
• Role of Viruses in the Pathogenesis of Pulmonary Fibrosis
  Gary Hunninghake and Lois Geist
• Current Treatment Options (Medical Therapy, Lung Transplantation)
  R. M. du Bois and G. P. Westall
• Future Directions in Therapy
  Marvin Schwarz
• Future Directions in Genetic Strategies for Understanding and Treating Pulmonary Fibrosis
  Ronald G. Crystal.