BASIC AND CLINICAL PHARMACOLOGY

The most current, authoritative, and comprehensive pharmacology book for medical, pharmacy, and other health science students. Widely respected for its clarity, comprehensiveness, and organization, this pharmacology course book presents the essential concepts that students need to know about the science of pharmacology and their application. Focuses on the basic principles of each drug group as well as the clinical choice and use of drugs in patients and the monitoring of their effects.

Puntos Clave

• The most current and authoritative pharmacology text
• Concise and thorough introduction to basic and clinical pharmacology
• All chapters rigorously updated with new drugs and references
• Unique chapter on botanicals (herbal medications) and nutritional supplements
• Special-interest boxes
• Lists of commercial preparations available, including trade and generic names and dosage formulations, featured at the end of each chapter
• Revised every 3 years, this book is respected for its clarity, comprehensiveness, and organization
• Presents the essential concepts that students need to know about the science of pharmacology and the clinical application of these concepts to patient care
• Provides state-of-the art information
• Provides an evidence-based approach to the pharmacology and clinical efficacy of commonly used and commercially available substances
• Explain valuable clinical points that build upon the concepts presented in the chapters
• Provides easy reference for writing chart orders or prescriptions

Tabla de Contenidos

• I. BASIC PRINCIPLES 1. Introduction 2. Drug Receptors & Pharmacodynamics 3. Pharmacokinetics & Pharmacodynamics: Rational Dosing & the Tiem Course of Drug Action 4. Drug Biotransformation 5. Basic & Clinical Evaluation of New Drugs
• II. AUTONOMIC DRUGS 6. Introduction to Autonomic Pharmacology 7. Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugs 8. Cholinoceptor-Blocking Drugs 9. Adrenoceptor-Activating & Other Sympathomimetic Drugs 10. Adrenoceptor Antagonist Drugs
• III. CARDIOVASCULAR-RENAL DRUGS 11. Antihypertensive Agents 12. Vasodilators & the Treatment of Angina Pectoris 13. Cardiac Glycosides & Other Drugs Used in Congestive Heart Failure 14. Agents Used in Cardiac Arrhythmias 15. Diuretic Agents
• IV. DRUGS WITH IMPORTANT ACTIONS ON SMOOTH MUSCLE 16. Histamine, Serotonin, & the Ergot Alkaloids 17. Vasoactive Drugs 18. The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds 19. Nitric Oxide, Donors, & Inhibitors 20. Drugs Used in Asthma
• V. DRUGS THAT ACT IN THE CENTRAL NERVOUS SYSTEM 21. Introduction to the Pharmacology of CNS Drugs 22. Sedative-Hypnotic Drugs 23. The Alcohols 24. Antiseizure Drugs 25. General Anesthetics 26. Local Anesthetics 27. Skeletal Muscle Relaxants 28. Pharmacologic Management of Parkinsonism & Other Movement Disorders 29. Antipsychotic Agents & Lithium 30. Antidepressant Agents 31. Opioid Analgesics & Antagonists 32. Drugs of Abuse
• VI. DRUGS USED TO TREAT DISEASES OF THE BLOOD, INFLAMMATION, & GOUT 33. Agents Used in Anemias; Hematopoietic Growth Factors 34. Drugs Used in Disorders of Coagulation 35. Agents Used in Hyperlipidemia 36. Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout
• VII: ENDOCRINE DRUGS 37. Hypothalamic & Pituitary Hormones 38. Thyroid & Antithyroid Drugs 39. Adrenocorticosteroids & Adrenocortical Antagonists 40. The Gonadal Hormones & Inhibitors 41. Pancreatic Hormones & Antidiabetic Drugs 42. Agents That Affect Bone Mineral Homeostasis
• VIII: CHEMOTHERAPEUTIC DRUGS 43. Beta-Lactam Antibodies & Other Inhibitors of Cell Wall Synthesis 44. Chloramphenicol. Tetracyclines, Macrolides, Clindamycin, & Streptogramins 45. Aminoglycosides & Spectinomycin 46. Sulfonamides, Trimethoprim, & Quinolones 47. Antimycobacterial Drugs 48. Antifungal Drugs 49. Antiviral Agents 50. Miscellaneous Antimicrobial Drugs: Disinfectants, Antiseptics, & Sterilants 51. Clinical Use of Antimicrobial Agents 52. Basic Principles of Antiparasitic Chemotherapy 53. Antiprotozoal Drugs 54. Clinical Pharmacology of the Anthelmintic Drugs 55. Cancer Chemotherapy 56. Immunopharmacology
• IX. TOXICOLOGY 57. Introduction to Toxicology: Occupational & Environmental 58. Heavy Metal Intoxication & Chelators 59. Management of the Poisoned Patient
• X. SPECIAL TOPICS 60. Special Aspects of Perinatal & Pediatric Pharmacology 61. Special Aspects of Geriatric Pharmacology 62. Dermatologic Pharmacology 63. Drugs Used in Gastrointestinal Diseases 64. Therapeutic & Toxic Potential of Over-the-Counter Agents 65. Botanicals (¿Herbal Medications¿) & Nutritional Supplements 66. Rational Prescribing & Prescription Writing
• Appendix I. Vaccines, Immune Globulins, & Other Complex Biologic Products Appendix II. Important Drug Interactions & Their Mechanisms